采用光遗传进行点燃行癫痫研究
Cortical EEG and hippocampal depth electrode activity with prefrontal cortex glutamate changes during kindling stimulation with blue (445 nm) light in a transgenic mouse from Jackson Laboratory expressing channelrhodopsin.
Light pulses (20 Hz, 10% duty cycle, 600 mA) were delivered for 20 seconds. The blue LED power measured prior to implant was 130 mW/mm2 .
Application of 40 Hz stim frequency (10% duty cycle, 600 mA) 10 seconds ON, 10 seconds OFF periods for one hour intervals (blue bars) results in increased power in the Gamma frequency (25-50 Hz) range and decreased NREM sleep by an average of 42 percent during time when stim was applied
软件
癫痫分析软件
自动癫痫发作识别、热密度图谱、光谱图、时间分析、功效分析
癫痫统计: 平均持续时间、 癫痫发作间隔时间、峰值频率等
动物活动视频跟踪分析, 活动实时跟踪记录
睡眠分析软件
三种睡眠评分手段: 手动、簇、阈值评分
实时睡眠图(hypnograms)、波谱图、热点图辅助评判睡眠状态。功效分析、峰值频率分析
上海塔正科技有限公司
经营模式:
所在地区:上海 松江区
成立时间: 2018年